Read the latest news from the Feinberg Cardiovascular Research Institute. The links below take you to articles where you can learn more about our latest achievements and news, as well as our investigators' awards and honors.
A team of scientists has discovered that mutations in the genes FOXC2 and GJC2 are associated with defects in venous valves, flaps within veins that help maintain proper blood flow.
The study, published in the Journal of Experimental Medicineand led by investigators at King’s College London, was co-authored by Tsutomu Kume, PhD, professor of Medicine in the Division of Cardiology and of Pharmacology.
- 05.17.2017A new study, published in Science Signaling, provides a surprising preventive role of reactive oxygen species (ROS) against preeclampsia. Preeclampsia is a pregnancy complication characterized by the acute onset of hypertension and proteinuria. Preeclampsia accounts for 10-15% of maternal death and around 4-5% stillbirth all over the world. A Northwestern scientist, Dr. Tomokazu Souma (Quaggin Lab) in collaboration with researchers in Tohoku University, University of Tsukuba, and Harvard medical school identified beneficial/preventive role of reactive oxygen species (ROS) in pathogenesis of preeclampsia using a mouse model. Increasing oxidative stress by depleting a cellular antioxidant stress pathway improves both maternal and fetal outcomes. Conversely, reducing oxidative stress worsens the outcomes. The results may explain the largely negative results of clinical trials for antioxidants in prevention of preeclampsia. Read the paper in Science Signaling
- 03.20.2017Northwestern Medicine scientists have revealed the role of a protein, SNRK, in cardiac tissue metabolism, which may lead to new insights in treating heart failure.
- 2017 Cardiovascular Research Day02.24.2017
2017 FCVRI Cardiovascular Research Day